Form: EFFECT

Notice of Effectiveness

June 21, 2012

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

Notice of Effectiveness

Effectiveness Date: June 21, 2012 4:00 P.M.
Form: S-1
CIK: 0001124524
Company Name: Cryoport, Inc.
File Number: 333-180326