Form: EFFECT

Notice of Effectiveness

December 29, 2010

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

Notice of Effectiveness

Effectiveness Date: December 29, 2010 10:30 A.M.
Form: S-1
CIK: 0001124524
Company Name: Cryoport, Inc.
File Number: 333-170027