Form: EFFECT

Notice of Effectiveness

February 25, 2010

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

Notice of Effectiveness

Effectiveness Date: February 25, 2010 9:00 A.M.
Form: S-1
CIK: 0001124524
Company Name: Cryoport, Inc.
File Number: 333-162350