Form: EFFECT

Notice of Effectiveness

January 25, 2008

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

Notice of Effectiveness

Effectiveness Date: January 25, 2008 4:00 P.M.
Form: SB-2
CIK: 0001124524
Company Name: Cryoport, Inc.
File Number: 333-147300